When my Mom and I Skype I keep up with the goings on in the small MO town where she lives. A friend/extended family member went on vacation for the first time in decades, and Mom and my Aunt were in charge of feeding the cats, Mom in the evenings and Aunt in the mornings. The lady has a cat door and apparently other openings to the outside that hadn't been an issue when she was there every day. However, turns out that 2 opposums decided they had found heaven with her gone, and moved in. There were countless messes each day, and her son was called in to help with a trap, which didn't work.
When the lady returned, she cocked her bb gun as far as she can (she's in her late 80's and small but wiry) and when she heard them the first night she was back, she crept down the hall and popped one in the head. Didn't phase it.
Now she's got the rifle out. He great-grandson told her she can't shoot that in the house! She says it's her house, she can if she wants. Family members descended with more traps... I'll keep you updated.